BACKGROUND: DFR (different region) analysis has been developed for typing Yesinia pestis in our previous study, and in this study, we extended this method by using 23 DFRs to investigate 909 Chinese Y.pestis strains for validating DFR-based genotyping method and better understanding adaptive microevolution of Y.pestis.METHODOLOGY/PRINCIPAL FINDINGS
The methodology carried out in this work is based on non-parametric inference.The problem is framed as a regression analysis, and the solution is derived using the permutation approach.The proposed test does not rely on the assumption that the distribution of the response follows a specific family of probability laws, unlike other parametric approa
Pregnancy is a physiological condition characterized by a progressive increase of the different components of the renin-angiotensin system (RAS).The physiological consequences of the Mittens stimulated RAS in normal pregnancy are incompletely understood, and even less understood is the question of how this system may be altered and contribute to th
The analysis of data variability from in-situ observations is essential for scientists and space mission controllers.Given the limited resources available on-board a spacecraft as well as the presence of the Field-Programmable Gate Arrays (FPGA) devices in modern spacecraft architectures, an efficient real-time monitoring solution should be deploye